Stars Air Ambulance was called to the scene of a serious crash on the Perimeter Highway Wednesday morning. 

Emergency crews were called to the south Perimeter Highway at Brady Road, shortly after 8 a.m. 

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RCMP say a pickup truck travelling westbound on the Perimeter, jumped the median and collided head-on with an eastbound van.

It is unclear at this time as to how many people were injured and the extent of their injuries.

However, RCMP have confirmed that the crash was fatal.

As a result, the eastbound lanes of the south Perimeter have been shut down at Brady Road.

Motorists are asked to avoid the area until further notice.

Manitoba RCMP continues to investigate the cause of the collision.